Chromosome segregation relies on kinetochores that assemble on specialized centromeric chromatin containing a histone H3 variant. In budding yeast, a single centromeric nucleosome containing Cse4 ...
Cancer’s epigenetic landscape, a labyrinthine tapestry of molecular modifications, has long captivated researchers with its profound influence on gene expression and cellular fate. This review ...
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Creative Commons (CC): This is a Creative Commons license. Attribution (BY): Credit must be given to the creator. The transition from B-DNA to A-DNA occurs in many protein–DNA interactions or in ...
Figure 2: Nucleosome dynamics and mixing of parental and new H3–H4 dimers. Figure 3: Fate of old and new H3–H4 dimers and their marks at the fork. In summary, several models that are not ...
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Octamers eluate first, at approximately 62.5 mL, then H3-H4 tetramers and H2A-H2B dimers at approximately 70 and 82 mL ... according to the manufacturer’s instructions (Figure 2D). Samples are ...