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烯醇结构的羟基氧上一对P电子和碳碳双键中的π键形成P-π共轭体系，使电荷在一定程度上偏向碳端，增加了羟基氧氢键的极性，使氢更容易离去（pKa：10.94），不好理解的话可以参考苯酚结构。氢离子离去后形成烯醇负离子是一个三原子四电子的共轭体系 ...

Faculty of Chemistry, University of Wroclaw, ul. F. Joliot-Curie 14, 50-383 Wroclaw, Poland ...

酒精性肝病（ALD）中脂质稳态失衡是关键问题。研究人员围绕 AKAP12-PKA 轴在 ALD 脂质稳态调控的作用展开研究。结果发现，该轴能调节脂质信号，其失衡会加重脂肪变性。这为 ALD 治疗提供新靶点，对理解 ALD 发病机制和开发新疗法意义重大。 在酒精的 “侵袭 ...

Ibuprofen is a relatively weak acid (pka 4.4) and its solubility in water or at acid pHis very low. This results in a relatively long residence time in the acid environment of the stomach ...

A 70-year-old man named Dwarika Prasad died after being hit by a car on National Highway NH2 in Kaushambi district. The driver fled the scene, and passersby took Prasad to the hospital, where he was ...

College of Materials and Chemical Engineering, Key Laboratory of Inorganic Nonmetallic Crystalline and Energy Conversion Materials, China Three Gorges University, Yichang 443002 Hubei, China Hubei ...

Autonomous University of San Luis Potosi, San Luis Potosi, Mexico.. National Center for Toxicological Research/FDA, Jefferson, USA;. The role of free fatty acids (FFAs) as a source of energy and their ...