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At the AD/PD meeting held last month in Vienna, scientists implicated T lymphocytes—specifically, the cytotoxic, CD8-positive variety—in Alzheimer’s disease. While the modus operandi of these cells in ...

Cells, are you experiencing stress? Quick, SUMOylate your TDP-43 before it’s too late! Three independent papers appearing in rapid succession deliver the same message: Chain the small ubiquitin-like ...

Because hypertension is linked to a greater risk of dementia, several trials have investigated whether lowering blood pressure in older people would protect the brain. Data from cohorts of a few ...

First trial of concurrent amyloid and tau immunotherapies in sporadic Alzheimer’s is underway. Safety data are a go for subcutaneous remternetug. Plaque removal correlates with cognitive benefit in ...

Ph.D., SUNY Downstate Medical Center & NYS Institute for Basic Research, NY, USA. M.D., Aga Khan University, Karachi, Pakistan ...

Undergraduate in psychology at UFCSPA.

The association between vaccination against the herpes zoster (HZ) virus, which causes shingles, and dementia risk continues to gain traction. Earlier this month, Pascal Geldsetzer and his team at ...

Tauopathies are a class of neurodegenerative disorders characterized by abnormal aggregation of the tau protein, encoded by the MAPT gene. These include frontotemporal dementia, Pick’s, and ...

As the trained killers of the immune system, cytotoxic T cells silently save our lives every day—vanquishing viruses before they can run amok, and putting nascent cancer cells out of business before ...

Cytotoxic T cells are star players in the adaptive immune system, enforcing protection against invading viruses or cancer cells. However, evidence has been mounting that the cells may also deal a ...

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