Neuropeptide Y (NPY) is a 36 amino-acid neuropeptide that is involved in various physiological and homeostatic processes in both the central and peripheral nervous systems. It is secreted alongside other neurotransmitters such as GABA and glutamate .

2024年7月31日 · In stress adaptation, neuropeptide Y interacts with major biological pathways, including the hypothalamic-pituitary-adrenal axis and the autonomic nervous system. Neuropeptide Y counteracts the actions of corticotropin-releasing hormone (CRH), displaying anxiolytic effects.

Neuropeptide Y (NPY) is a 36-amino acid peptide with structural similarities to peptide YY (PYY) and pancreatic polypeptide (PP).

2006年1月1日 · Neuropeptide Y (NPY), a 36‐amino‐acid peptide is abundantly expressed throughout the mammalian nervous system including: neocortex, hippocampus, striatum, amygdala, hypothalamus, thalamus, and brain stem. NPY has been implicated in …

2022年1月1日 · Neuropeptide Y (NPY) is a 36 amino acid polypeptide with tyrosine residues at both ends of the molecule. It is characterized structurally by a “PP-fold” consisting of an extended polyproline helix and an α-helix connected by a β-turn.

2021年8月3日 · Neuropeptide Y (NPY), one of the most abundant neuropeptides in the body, is widely expressed in the central and peripheral nervous systems and acts on the cardiovascular, digestive, endocrine, and nervous systems.

2019年8月19日 · Neuropeptide Y (NPY) is a neurotransmitter or neuromodulator that mainly exists in the nervous system. It plays a neuroprotective role in organisms and widely participates in the regulation of various physiological processes in vivo.

2018年9月18日 · Neuropeptide Y (NPY) is an abundant sympathetic co-transmitter, widely found in the central and peripheral nervous systems and with diverse roles in multiple physiological processes.

Neuropeptide Y (NPY) is a 36-amino acid peptide that plays a significant role in various physiological processes, including neuroimmune interactions. It is widely distributed in the brain and...

2023年10月9日 · Neuropeptide Y (NPY) is a principal neurotransmitter found in the central and peripheral nervous systems and is predominantly found in sympathetic neurons [8-10]. Peptide YY (PYY) has been localized to enteroendocrine cells in the mucosa of the gastrointestinal tract and is most highly concentrated in the ileum and colon [11].