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Pathology Outlines - Pulmonary artery intimal sarcoma
2024年1月26日 · The mitotic activity is 12 mitoses/10 high power fields. The tumor cells are positive for SMA, vimentin and CD31; negative for cytokeratin, desmin, myogenin, CD34, beta …
Pathology Outlines - Myxoid liposarcoma
2023年6月12日 · EWSR1 FISH will be positive but can lead to confusion with the 2 - 5% of myxoid liposarcomas that rarely have EWSR1 rearrangements PCR applications can be …
Pathology Outlines - Pleomorphic liposarcoma
2025年1月22日 · Pleomorphic sarcoma is a high grade sarcoma characterized by complex molecular alterations. The tumors show complex karyotypes with numerous cytogenetic …
Pathology Outlines - Nodular fasciitis
2024年9月25日 · USP6 rearrangement can be confirmed by FISH, PCR or next generation sequencing Radiology description Imaging findings, including MRI, are nonspecific and may …
Pathology Outlines - STAT6
2024年8月27日 · Cytogenetics / FISH studies may miss inversion breakpoints due to close proximity of NAB2 and STAT6 genes (Genes Chromosomes Cancer 2013;52:873) Common …
(FISH) FISH uses a fluorescently labeled probe targeted towards a specific genetic sequence. The fluores-cent probe can then be assessed in situ using a fluorescence microscope. Dual …
Pathology Outlines - Cemento-ossifying fibroma / ossifying fibroma
6 天之前 · Amplification of MDM2 gene by fluorescence in situ hybridization is rarely (3%) seen in ossifying fibroma (Head Neck Pathol 2022;16:991) Positive MDM2 amplification in craniofacial …
Pathology Outlines - Plasmacytoma
33 year old woman presented with vertigo and peripheral facial nerve palsy (World Neurosurg 2020;134:10) 47 year old man, previously diagnosed with chronic osteomyelitis, presented …
• Amplification of the MDM2 gene detectable by IHC/FISH/NGS is helpful for confirming a diagnosis of atypical lipomatous tumor/ well-differentiated liposarcoma (~93%) or …
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2024年8月27日 · Lymphoplasmacytic lymphoma (LPL) is a B cell neoplasm of small lymphocytes, plasmacytoid lymphocytes and plasma cells