磺达肝癸钠注射液，用于进行下肢重大骨科手术如髋关节骨折、重大膝关节手术或者髋关节置换术等患者，预防静脉血栓栓塞事件的发生。 用于无指征进行紧急 (<120分钟)侵入性治疗（PCI)的不稳定性心绞痛或非ST段抬高心肌梗死 (UA/NSTEMI)患者的治疗。 用于使用溶栓或初始不接受其它形式再灌注治疗的ST段抬高心肌梗死患者的治疗。 本品活性成分为磺达肝癸钠。

Fondaparinux is used to prevent blood clots after certain hip, knee, or stomach surgeries. It can also treat blood clots in the legs or lungs when given with another medicine called warfarin....

2024年11月11日 · Fondaparinux sodium injection is a Factor Xa inhibitor (anticoagulant) indicated for: Prophylaxis of deep vein thrombosis: fondaparinux sodium 2.5 mg subcutaneously once daily after hemostasis has been established. The initial dose should be given no earlier than 6 to 8 hours after surgery and continued for 5 to 9 days.

Fondaparinux (trade name Arixtra) is an anticoagulant medication chemically related to low molecular weight heparins. It is marketed by Viatris. A generic version developed by Alchemia is marketed within the US by Dr. Reddy's Laboratories.

本品用于进行下肢重大骨科手术如髋关节骨折、重大膝关节手术或者髋关节置换术等患者，预防静脉血栓栓塞事件的发生。 进行重大骨科 手术 的患者：本品推荐剂量为每日1次2.5mg，术后皮下注射给药。 初始剂量应在手术结束后6小时给予，并且需在确认已止血的情况下。 治疗应持续到 静脉血栓 栓塞风险消失以后，通常到患者可以下床活动，至少在手术后5-9天。 临床经验显示：进行髋关节 骨折 手术的患者，发生静脉血栓栓塞的危险将持续至手术后9天以上。 对于这些患者， …

View fondaparinux sodium information, including dose, uses, side-effects, renal impairment, pregnancy, breast feeding, contra-indications and directions for administration.

Fondaparinux injection is used to prevent deep vein thrombosis (DVT; a blood clot, usually in the leg), which can lead to pulmonary embolism (PE; a blood clot in the lung), in people who are having hip surgery, hip or knee replacement, or abdominal surgery. It is also used in along with warfarin (Coumadin, Jantoven) to treat DVT or PE.

2024年4月10日 · Fondaparinux is recommended by ACCP as one of several anticoagulant options for VTE prophylaxis in patients undergoing major orthopedic surgery. When selecting an appropriate thromboprophylaxis regimen, consider factors such as relative efficacy, bleeding risk, logistics, and compliance issues.

磺达肝癸钠是根据肝素与抗凝血酶Ⅲ特异性结合序列而人工合成的戊多糖，为活化因子Ⅹ选择性抑制剂。 磺达肝癸钠可特异而快速地与血浆中的抗凝血酶Ⅲ结合，导致后者的构象改变，从而使其与FⅩa的亲和力大大提高。 当抗凝血酶Ⅲ与FⅩa结合后，磺达肝癸钠则从复合物中解离出来，可继续活化其他的抗凝血酶Ⅲ分子。 磺达肝癸钠为短链结构，分子量仅为1728，因此并不增强抗凝血酶Ⅲ对凝血酶的抑制活性。 由于其完全为人工合成，并不含有动物源性成分，因此并不会导 …

2024年7月5日 · Fondaparinux is used to prevent a type of blood clot called deep vein thrombosis (DVT), which can lead to blood clots in the lungs (pulmonary embolism). A DVT can occur after certain types of surgery. Fondaparinux is also used together with warfarin (Coumadin, Jantoven) to treat DVT, including pulmonary embolism.