DNA supercoiling refers to the amount of twist in a particular DNA strand, which determines the amount of strain on it. A given strand may be "positively supercoiled" or "negatively …

In this review we will focus on the role of DNA supercoiling in the cellular processes, with particular emphasis on transcription.

2024年11月23日 · DNA supercoiling refers to the over- or under-winding of a DNA strand, and is an expression of the strain on that strand. Supercoiling is important in a number of biological …

The DNA can coil up into a "supercoil" topology and maintain the desired twist value (10.6) with the given linking number (475 in this case). The duplex can exist with a twist of 10.6 bp/turn for …

Supercoiling is a fundamental property of DNA and chromatin. It is modulated by polymerase and topoisomerase activities and, through regulated constraint, by DNA/chromatin binding proteins.

This results in the creation and accumulation of overwound (positively supercoiled) DNA ahead of the polymerases and underwound (negatively supercoiled) DNA behind. The positive …

2022年3月30日 · DNA supercoiling is a higher-order organization of DNA which is known as DNA packaging. It allows the winding and interwinding of DNA on and with one another. This …