Balancer chromosomes (or simply balancers) are a type of genetically engineered chromosome used in laboratory biology for the maintenance of recessive lethal (or sterile) mutations within …

A balancer chromosome is an engineered construct that ideally has three traits: (1) one or more DNA inversions to suppress the recovery of recombination products when a recombination …

Balancer chromosomes are an essential and powerful part of a fly geneticist's toolbox. They are used to maintain deleterious mutations in stable stocks as well as to prevent recombination …

2019年11月7日 · Balancer chromosomes are multiply inverted and rearranged chromosomes that are widely used in Drosophila genetics. First described nearly 100 years ago, balancers are …

Genetic balancers are genetic constructs or chromosomal rearrangements that allow lethal or sterile mutations to be stably maintained in heterozygotes. In this chapter we use the term …

This study details a new methodology of producing balancer chromosomes using CRISPR/Cas9 gene editing technology to create new inversions within the largest segment of the common X …

Balancer chromosomes are multiply inverted chromosomes that suppress meiotic crossing over and prevent the recovery of crossover products. Balancers are commonly used in Drosophila …

2022年7月25日 · A balancer chromosome has a few key properties that make it possible to reliably maintain a gene of interest (such as a mutation) over time: Multiple inverted DNA …

2019年11月7日 · Balancer chromosomes are multiply inverted and rearranged chromosomes that are widely used in Drosophila genetics. First described nearly 100 years ago, balancers are …

Balancer chromosomes are genetic reagents that are used in Drosophila melanogaster for stock maintenance and mutagenesis screens 1. Despite their utility, balancer...