Glucose transporter 2 (GLUT2) also known as solute carrier family 2 (facilitated glucose transporter), member 2 (SLC2A2) is a transmembrane carrier protein that enables protein …

GLUT2 controls the number of pancreatic islet cells and the volume of relevant organs during the development phase of the body; after maturation, GLUT2 regulates blood glucose through the …

2023年6月26日 · Under physiological conditions, GLUT2 transports glucose into cells and allows the glucose concentration to reach balance on the bilateral sides of the cellular membrane; …

Individuals with a missense mutation in GLUT2 show preference for sugar-containing foods. We will discuss how studies in mice help interpret the role of GLUT2 in human physiology.

GLUT2 has the unique characteristic among glucose transporters to have a low apparent affinity for glucose (Km ~17mM). It can also transport galactose (Km ~ 92 mM), mannose (Km ~125 …

The reduction of glucose in the blood results from the action of insulin. Glucose enters the beta cells of the pancreas through the glucose transporter GLUT2 and this is a major signal leading …

2014年11月25日 · Genome-wide association studies have reported that GLUT2 variants increase the risks of fasting hyperglycaemia, transition to type 2 diabetes, hypercholesterolaemia and …

Human GLUT2 and GLUT3, members of the GLUT/SLC2 gene family, facilitate glucose transport in specific tissues. Their malfunction or misregulation is associated with serious diseases, …

2009年5月1日 · By controlling GLUT2 transcription, the glucose influences its own metabolism, but GLUT2 is also involved in other aspects of diet sugar managing. From Genotype to …

2012年12月4日 · Kang and colleagues reported that although glucosensing neurons and nonglucosensing neurons express GLUT2 and GLUT4, single-cell RT-PCR showed that …