2022年9月15日 · Oxidized cholesterol is made in the body when low-density lipoprotein (LDL), sometimes called “bad” cholesterol, goes through a chemical reaction. Oxidized cholesterol is what builds up on the artery walls, the muscular tubes that carry blood away from the heart.

The oxidized LDL test may be ordered for individuals at low or intermediate risk of metabolic syndrome or cardiovascular disease. In addition, this test is useful in individuals who have cardiovascular disease and are at risk for an adverse cardiac event.

Oxidized low-density lipoprotein (Ox-LDL) has been studied for over 25 years. Numerous pro- and anti-atherogenic properties have been attributed to Ox-LDL. Yet, Ox-LDL has neither been defined nor characterized, as its components and composition change depending on its source, method of preparation, storage, and use.

2018年9月17日 · Research is still being conducted on oxidized LDL and the best treatment. The best defense is a healthy diet and lifestyle, so talk to your doctor and get on board.

LDL oxidation is undoubtedly an important atherogenic modification of native LDL, that takes place mostly in the vascular wall. Oxidation has been believed to be the only modification, i.e., responsible for the atherogenic properties of LDL particles for decades.

2024年10月15日 · Oxidized LDL cholesterol can build up against the artery cells, causing dangerous complications such as atherosclerosis. Learn more about the dangers of oxidized cholesterol.

2024年8月13日 · Oxidized cholesterol is the oxidation of low-density lipoprotein (LDL) cholesterol, which can build up as plaque in the walls of the arteries.

Oxidized LDL (oxLDL) represents a variety of modification of both lipid and apolipoprotein B (apoB) components by lipid peroxidation. This promotes atherosclerosis through inflammatory and immunologic mechanisms that lead to the formation of macrophage foam cells.

The term “Oxidized low-density lipoprotein” (ox-LDL) generally refers to a particle derived from circulating LDL that may have undergone oxidation toward one or both its main components, namely apoprotein and lipids.

Oxidized LDL (oxLDL) is known to be associated with excessive inflammation and abnormal lipoprotein metabolism. Chronic inflammatory diseases confer an elevated risk of premature atherosclerosis and adverse cardiovascular events.