2024年4月5日 · Effective management of systemic sclerosis requires early diagnosis and ongoing disease progression monitoring. Although a definitive cure does not exist for systemic sclerosis, treatment primarily focuses on managing affected organs and alleviating symptoms to prevent further organ damage in individuals with systemic sclerosis.

Systemic scleroderma, or systemic sclerosis, is an autoimmune rheumatic disease characterised by excessive production and accumulation of collagen, called fibrosis, in the skin and internal organs and by injuries to small arteries. There are two major subgroups of systemic sclerosis based on the extent of skin involvement: limited and diffuse ...

2024年6月15日 · Scleroderma (sklair-oh-DUR-muh), also known as systemic sclerosis, is a group of rare diseases that involve the hardening and tightening of the skin. Scleroderma also may cause problems in the blood vessels, internal organs and digestive tract.

There are five stages of scleroderma symptom development and progression. Systemic sclerosis has the highest mortality rate among systemic autoimmune diseases due to pulmonary hypertension, pulmonary fibrosis (interstitial lung disease), and scleroderma renal crisis.

Progressive systemic sclerosis, also known as systemic sclerosis or scleroderma, is a rare autoimmune disease that affects the skin and internal organs. In this condition, the body's immune system mistakenly attacks healthy tissues, leading to inflammation and the hardening and tightening of the skin and connective tissues.

2024年1月22日 · It is a long-lasting (chronic) autoimmune disorder, an illness in which the body's immune defenses mistakenly attack the body's own cells rather than protecting them from outside invaders. Scleroderma also is called progressive systemic …

Two-thirds of patients with systemic sclerosis have dcSSc: skin involvement is widespread and includes proximal limbs. DcSSC is often rapidly progressive, with significant internal organ involvement.

Systemic sclerosis, also known as scleroderma, is a rare and complex autoimmune connective-tissue disease. Once considered an untreatable and unpredictable condition, research advancements have improved our understanding of its disease pathogenesis and clinical phenotypes and expanded our treatment armamentarium.

2023年6月27日 · Systemic scleroderma is also known as systemic sclerosis (SSc) and can lead to serious or even life-threatening organ damage and complications. In some patients, scleroderma is localized and purely a skin disorder, at times characterized by isolated patches of thickened, scarred, tight skin.

Systemic sclerosis (SSc) is a systemic, immune-mediated chronic disorder characterized by small vessel alterations and progressive fibrosis of the skin and internal organs. The combination of a predisposing genetic background and triggering factors that causes a persistent activation of immune system at microvascular and tissue level is thought ...