In biochemistry, sulfotransferases (SULTs) are transferase enzymes that catalyze the transfer of a sulfo group (R−SO− 3) from a donor molecule to an acceptor alcohol (R−OH) or amine (R−NH2). [1] . The most common sulfo group donor is 3'-phosphoadenosine-5'-phosphosulfate (PAPS).

A Sulfotransferase is an enzyme that transfers a sulfonate group from PAPS to hydroxyl groups of acceptor molecules. They can be classified into two groups based on their cellular localization: membrane-associated enzymes that act on macromolecules, and soluble enzymes that act on small organic molecules like flavonoids and neurotransmitters.

Estrogen sulfotransferase (SULT1E1, also known as EST), widely expressed in human tissues such as the liver, lung, adipose tissue, and kidney (Barbosa et al., 2019), is best known for its function in the sulfoconjugation and deactivation of estrogens.

2004年7月5日 · Early studies of sulfotransferases (STs), the enzymes that catalyze sulfonation, focused primarily on the cytosolic STs, which are involved in detoxification, hormone regulation, and drug metabolism. Although known to exist, the membrane-associated STs were not studied as extensively until more recently.

2005年12月1日 · Sulfonation is an important reaction in the metabolism of numerous xenobiotics, drugs, and endogenous compounds. A supergene family of enzymes called sulfotransferases (SULTs) catalyze this reaction. In most cases, the addition of a sulfonate moiety to a compound increases its water solubility and decreases its biological activity.

磺基转移酶（sulfotransferase）是2008年公布的生物化学与分子生物学名词。 编号：EC 2.8.2.-。 催化硫酸基团从3′-磷酸腺苷酰硫酸上转移给各种受体分子的酶。 编号：EC2.8.2.-。 催化硫酸基团从3′-磷酸腺苷酰硫酸上转移给各种受体分子的酶。 《生物化学与分子生物学名词》。 磺基转移酶（sulfotransferase）是2008年公布的生物化学与分子生物学名词。

Sulfotransferases catalyze the formation of sulfuric acid esters, most often referred to as sulfates, from a wide range of xenobiotics and their metabolites, as well as various endogenous neurotransmitters, hormones, bile acids, carbohydrates, and proteins.

Sulfotransferase is an important enzyme family that catalyses the transfer of a sulfate group from a donor substrate, 3′-phosphoadenosine-5′-phosphosulphate (PAPS), to an acceptor substrate which may be a drug, a hormone or a neurotransmitter that possesses a hydroxy or …

The human cystosolic sulfotransferases (SULTs) comprise a 13-member family of enzymes that catalyze transfer of the sulfuryl-group (–SO 3) from 3′-phosphoadenosine 5′-phosphosulfate (PAPS) to the hydroxyl and primary amine moieties of thousands of …

Sulfotransferases transfer sulfuryl groups in enzymatic reactions. Several different sulfotransferase enzymes. Cells are master chemists. They perform all manner of chemical reactions to build and modify their molecules. One of the chemical tricks used by many cells is to add sulfuryl groups to a molecule.