2022年5月17日 · Tumor has 2 basic components: fibrous stroma and bone trabeculae Zonation pattern is a characteristic feature In the center, the lesion is more fibrous and the newly formed …

2022年12月21日 · Neoplastic bone (necessary for diagnosis): no minimum quantity necessary Most common: filigree / lace-like disorganized woven bone (intimately associated with …

2021年9月13日 · The cortical bone is focally destroyed and replaced by a reactive rim of woven bone at the tumor periphery. Immunohistochemical stains for H3.3 G34W and p63 are positive …

2021年12月10日 · Remodeling is a continuous process, in which damaged bone is repaired, ion homeostasis is maintained, and bone is reinforced for increased stress; entire remodeling …

2021年8月3日 · Admixture of mature lamellar and woven bone patterns, with Haversian-like canals, which may have various sizes and shapes (Nielson: Diagnostic Pathology - Bone, 2nd …

Mixture of reactive woven bone and fibrous tissue without zonation Typically arises in the periosteum of fingers Parosteal osteosarcoma: Similar location and age group More …

Lacks parallel streams of bone Lack of MDM2 gene amplification and immunohistochemistry is negative (Mod Pathol 2011;24:624) Low grade central osteosarcoma. Low grade spindle cell …

2022年7月21日 · Woven bone formation and osteoclast-like giant cells (Histopathology 1999;34:447) Rare mitotic figures Areas of conventional low grade chondrosarcoma can be …

2020年9月25日 · Dense cortical bone being replaced by cellular fibro-osseous material is also seen. The fibrous tissue exhibits spindle shaped cells that produce osteoid and spherical …

2016年12月1日 · Curvilinear trabeculae (Chinese letters) of metaplastic woven bone (never matures) in hypocellular, fibroblastic stroma Fibrous dysplasia is caused by mutations in …