Congenital ectropion uveae (CEU) (i.e. congenital iris ectropion syndrome, primary iris pigment epithelial hyperplasia) is a rare disorder with unilateral anterior chamber dysgenesis that commonly leads to unilateral secondary glaucoma in the mid-teenage years with associated morbidity and possible blindness.

2021年1月5日 · Rarely is ectropion present at birth (congenital). When it is, it's usually associated with genetic disorders, such as Down syndrome.

Congenital ectropion uveae is caused by genetic mutations, also known as pathogenic variants. Genetic mutations can be hereditary, when parents pass them down to their children, or they may occur randomly when cells are dividing.

2024年12月6日 · Congenital ectropion. This is a type of outward-turning eyelid that you’re born with. Down syndrome and blepharophimosis syndrome are two congenital conditions that may make ectropion more likely.

Congenital bilateral ectropion of the upper eyelids is a rare, benign condition reported in ophthalmic literature. It is more frequently associated with Down’s syndrome, ichthyosis, and sporadic cases in newborns from black population.

2021年7月21日 · Congenital entropion is a rare condition in which the lower eyelid margin is rotated inward since birth. Chronic entropion can cause chronic irritation, corneal scarring, and subsequent vision loss. Congenital entropion may be due to retractor malformation, structural defects in the tarsal plate, or shortening of the posterior lamella.

2023年8月25日 · Iris ectropion syndrome is a rare congenital anomaly. Congenital iris ectropion is caused by the developmental arrest of the neural crest, unlike Axenfeld Rieger syndrome and Peters anomaly, which are caused by disorders in the proliferation, migration, and differentiation of neural crest cells.

Isolated congenital ectropion is a rare ocular disease characterized by congenital, unilateral or bilateral, lower or upper eyelid malposition with eversion of the margin due to a vertical shortage of skin, leading to exposure of the conjunctiva and sometimes the cornea.

Congenital ectropion uveae is a rare, genetic, non-syndromic developmental defect of the eye characterized by the presence of iris pigment epithelium on the anterior surface of the iris, anterior insertion of the iris, angle dysgenesis and progressive open-angle glaucoma (the latter may present in infancy or may develop later in life).

Congenital (very rare) Pathophysiology. In involutional ectropion, the tarsoligamentous sling supporting the eyelid by attachment to the orbital rim via the medial and lateral canthal tendons becomes lax. In paralytic ectropion, orbicularis muscle tone is …