2025年1月27日 · Target identification is the initial stage of target-guided drug discovery and development [1], with applications ranging from predicting side-effect targets [2], discovering potential targets of ...

2016年12月2日 · Here, we present an updated comprehensive map of molecular targets of approved drugs. We curate a total of 893 human and pathogen-derived biomolecules through which 1,578 US FDA-approved drugs...

A drug target is a specific molecule, often a protein, in the body that is closely linked to a particular disease process and can be influenced by a drug to produce a desired therapeutic outcome. AI generated definition based on: Comprehensive Medicinal Chemistry II, 2007

TTD is a database providing information about the known and explored therapeutic protein and nucleic acid targets, the targeted disease, pathway information and the corresponding drugs …

This chapter lays out some formal definitions of a drug or medicine and introduces the concept of a drug target. It then describes the wide range of drug types that are being produced by the biopharmaceutical industry.

Access the world’s pharmaceutical knowledge database. Information on drugs, drug targets, and more, used by researchers and health professionals globally.

Here, we present an updated comprehensive map of molecular targets of approved drugs. We curate a total of 893 human and pathogen-derived biomolecules through which 1,578 US FDA-approved drugs act. These biomolecules include 667 human-genome-derived proteins targeted by drugs for human disease.

5 天之前 · Their work suggests a new target for treating anxiety disorders and related conditions and demonstrates a general strategy, based on a method called photopharmacology, for mapping drug effects on the brain.

Here, we present an updated comprehensive map of molecular targets of approved drugs. We curate a total of 893 human and pathogen-derived biomolecules through which 1,578 US FDA-approved drugs act. These biomolecules include 667 human-genome-derived proteins targeted by drugs for human disease.

2006年10月1日 · Here, we consider the nature of drug targets, and by classifying known drug substances on the basis of the discussed principles we provide an estimation of the total number of current drug...