GLP-1 (1-37 or 1-36) is further N-terminally truncated resulting in GLP-1 (7-37) or GLP-1- (7-36) which can be amidated. These GLP-1 peptides are known to enhance glucose-dependent …

Active GLP-1 protein secondary structure includes two α-helices from amino acid position 13–20 and 24–35 separated by a linker region. Alongside glucose-dependent insulinotropic peptide …

Individual amino acids stimulating GLP-1 secretion include glutamine, asparagine, phenylalanine, and glycine, with glutamine and glycine being the most potent [, , ]. When orally administered, …

Glucagon-like peptide-1(7-36)amide (GLP-1) is a 30-residue peptide hormone released from intestinal L cells following nutrient consumption. It potentiates the glucose-induced secretion of …

glucagon-like sequences: glucagon (PG 33-61), glucagon-like peptide- 1 (PG 78-107 amide), and glucagon-like peptide-2 (PG 126-158). The two latter sequences are separated by an …

1989年8月5日 · Judging from the small intestine by hydrophobic, gel permeation, and predicted amino acid sequence of the prohormone and from reverse-phase high performance liquid …

Here in our present study we synthesized a novel functional analogue of GLP-1 conjugated to tetramethyl rhodamine to monitor the internalization of the receptor. Our data shows that …

The availability of the amino acid sequences of GLP-1 and GLP-2 obtained from the decoding of the nucleotide sequences based on the genetic code allowed for the chemical synthesis of the …

Glucagon-like peptide-1 (GLP-1) promotes insulin secretion from pancreatic β-cells in a glucose dependent manner. Several pathways mediate this action by rapid, kinase...

Glucagon like peptide-1 (GLP-1) is a GI hormone produced in endocrine cells in the distal small intestine by alternative processing of the proglucagon gene product. In humans it is a 29 …