Glutamate inhibitors or glutamate antagonist drugs inhibit the action of neurotransmitter glutamate on neurons and are used to treat amyotrophic lateral sclerosis (ALS), also known as motor …

Current pharmacological options for MDD include the serotonin-selective reuptake inhibitors (SSRIs), serotonin norepinephrine reuptake inhibitors (SNRIs), atypical antidepressants (eg, …

2024年6月21日 · Glutamate antagonists are a fascinating and crucial class of drugs in the field of neuroscience and pharmacology. Understanding how these agents work and their applications …

NMDA (N-methyl-D-aspartate) receptor antagonists are a class of drugs that may treat memory loss and brain damage associated with Alzheimer’s disease. NMDA receptor allows the …

Glutamate receptors are responsible for the glutamate-mediated postsynaptic excitation of neural cells, and are important for neural communication, memory formation, learning, and regulation. …

Glutamate receptor antagonists can be broadly divided into two types: agents that block the NMDA receptor and those that block the AMPA receptor. Antagonists of the NMDA receptor …

Glutamate antagonists work by inhibiting the activity of glutamate receptors in the brain. These receptors are broadly classified into two main subtypes: N-methyl-D-aspartate (NMDA) and 3 …

Ketamine is a voltage-dependent NMDA receptor antagonist that inhibits the flux of cations (calcium, sodium) in the presence of the coagonists glutamate and glycine.

2024年4月11日 · The glutamate pathway antagonist riluzole is the first medication that has shown efficacy in extending life in amyotrophic lateral sclerosis (ALS). The American Academy of …

Serotonin reuptake inhibitors and benzodiazepines are evidence-based pharmacological treatments for Anxiety Disorders targeting serotonin and GABAergic systems, respectively. …