2023年5月17日 · Myocardial fibrosis is a condition that causes scar tissue to build up in your heart. It’s most common after a heart attack, but it can occur at other times as well.

2020年7月3日 · New UCLA research conducted in mice could explain why some people suffer more extensive scarring than others after a heart attack. The study, published in the journal Cell, reveals that a protein known as type 5 collagen plays a critical role in regulating the size of scar tissue in the heart.

2024年2月16日 · Myocardial fibrosis is a condition that involves the buildup of scar tissue in the myocardium, which is the heart muscle. Anything that causes damage to the heart can lead to scar tissue. Heart attacks are the most common cause of myocardial fibrosis. Both sudden heart injury and chronic heart injury due to disease can cause scar tissue to form.

The Impact of Scar Tissue on Heart Function. Scar tissue affects how well the heart performs its vital functions. The presence of fibrous tissue alters both mechanical and electrical properties: 1. Impaired Contractility. Healthy cardiac muscle contracts rhythmically and efficiently pumps blood throughout the body.

Myocardial scarring is the accumulation of fibrous tissue resulting after some form of trauma to the cardiac tissue. [1][2] Fibrosis is the formation of excess tissue in replacement of necrotic or extensively damaged tissue.

2023年1月13日 · Researchers have developed a method that could 'turn back the clock' on damaged heart tissue following heart attacks. After a heart attack, the shock of the event leaves behind a trail of damaged heart muscle, which becomes a scar over time.

For the first time, researchers from Massachusetts General Hospital have discovered a key to the zebrafish’s remarkable ability to reabsorb scar tissue, and regenerate heart cells, after injury; Scar tissue is permanent in mammals after a heart attack, leading to heart failure

Cardiac scars, often perceived as “dead” tissue, are very much alive, with heterocellular activity ensuring the maintenance of structural and mechanical integrity following heart injury. To form a scar, non-myocytes such as fibroblasts, proliferate ...

2024年8月22日 · Myocardial scar tissue or myocardial scar is referred to as the final result and pathological correlate of myocardial infarction or myocardial injury and typically develops from the infarcted myocardium.

2020年7月20日 · After a heart attack, the body’s repair system replaces damaged heart muscle with scar tissue. For reasons that aren’t well understood, some people develop much larger scars after a heart attack than others. People with larger scars have a higher risk of other heart problems and death.