2019年1月9日 · This Review discusses how the mitochondrial protein import machinery functions as a key organizer of these protein networks, its involvement in the formation of membrane …

Mitochondria are essential for the viability of eukaryotic cells as they perform crucial functions in bioenergetics, metabolism and signalling and have been associated with numerous diseases. …

Most of the proteins involved are grouped into three large respiratory enzyme complexes, each containing transmembrane proteins that hold the complex firmly in the inner mitochondrial …

Mitochondrial proteins refer to a subset of proteins that are synthesized in the cytoplasm from nuclear genes and imported into the mitochondrion through translocation complexes in the …

Mitochondrial proteins are proteins that reside within the mitochondria of cells, including within the cristae of the inner mitochondrial membrane.

Mitochondrial proteins are synthesized in the cytosol as precursor proteins containing specific targeting signals that dictate their route of import and final destination within the organelle. …

2023年10月31日 · Protein translocases are responsible for importing precursor proteins into mitochondria and form central elements of several protein interaction networks. These …

Mitochondrial proteins that are synthesized in the cytoplasm from nuclear genes are imported by translocation through translocation complexes in the mitochondrial membrane. Mitochondrial …

2021年2月16日 · These mitochondrially encoded proteins are key parts of the oxidative phosphorylation (OXPHOS) complexes, which produce ATP as a source of cellular chemical …

The phosphorylation of mitochondrial proteins has been connected with the dysregulation of mitochondrial functions that is found in neurodegenerative diseases, cancer, diabetes, heart …