Mosunetuzumab, sold under the brand name Lunsumio, is a monoclonal antibody used for the treatment of follicular lymphoma. [2][3][5] It bispecifically binds CD20 and CD3 to engage T-cells. [2][3] It was developed by Genentech.

LUNSUMIO (mosunetuzumab-axgb) is a prescription medicine used to treat adults with follicular lymphoma whose cancer has come back or did not respond to previous treatment, and who have already received two or more treatments for their cancer.

Mosunetuzumab-axgb is a T-cell engaging bispecific antibody that binds to the CD3 receptor expressed on the surface of T-cells and CD20 expressed on the surface of lymphoma cells and some...

2022年7月5日 · Mosunetuzumab is a CD20 × CD3 T-cell-engaging bispecific monoclonal antibody that redirects T cells to eliminate malignant B cells. In a phase 1 study, mosunetuzumab was well tolerated and active in patients with relapsed or refractory B-cell lymphoma.

2023年4月11日 · Mosunetuzumab is used to treat follicular lymphoma (a cancer of the lymphatic system) in adults whose cancer has returned or did not respond to another treatment and who …

On December 22, 2022, the Food and Drug Administration (FDA) granted accelerated approval to mosunetuzumab-axgb (Lunsumio, Genentech, Inc.), a bispecific CD20-directed CD3 T-cell engager for...

LUNSUMIO (mosunetuzumab-axgb) is indicated for the treatment of adult patients with relapsed or refractory follicular lymphoma after two or more lines of systemic therapy. This indication is …

2024年1月31日 · Mosunetuzumab-axgb injection is used to treat follicular lymphoma that has come back or did not respond to treatment in patients who have received at least 2 previous treatments.

Mosunetuzumab-axgb works by bringing healthy T cells (immune cells that help kill cancer cells) and lymphoma cells close together so the T cells can more effectively kill the lymphoma cells.

2023年1月2日 · What is this drug used for? It is used to treat a type of lymphoma. What do I need to tell my doctor BEFORE I take this drug? If you are allergic to this drug; any part of this drug; or any other drugs, foods, or substances. Tell your doctor about the allergy and what signs you had. If you are dehydrated, talk with your doctor.