Neural Crest Development - Embryology
3 days ago · Understand how neural crest cells contribute to the pharyngeal arches and the head structures they form. Neural Crest Derivatives. A key feature of neural crest is the migration into other embryonic tissues to form specific neural and non-neural populations and structures.
Tlx3 mediates neuronal differentiation and proper condensation …
Nov 1, 2024 · By combining lineage labeling with in situ hybridization in the chick embryo, we show that neural crest-derived cells that contribute to the cranial trigeminal ganglion express Tlx3 at a time point that coincides with the onset of ganglion condensation.
Developmental origins and evolution of jaws: new interpretation …
Dec 1, 2004 · The dorsal (maxillary, Mx) neural crest condensation has been proposed to give rise to palatoquadrate cartilage (PQ), which is often described to form the entire upper jaw, whereas the ventral (mandibulary, Md) condensation develops into Meckel's cartilage (MC) that is the lower jaw element.
The development, patterning and evolution of neural crest cell ...
Aug 1, 2020 · In this review, we focus on the chondrogenic and osteogenic potential of cranial neural crest cells and discuss the roles of Sox9, Runx2 and Msx1/2 transcription factors and WNT, FGF and TGFβ signaling pathways in regulating neural crest cell differentiation into cartilage and bone.
Making a head: Neural crest and ectodermal placodes in cranial …
Here, we review the origins of both neural crest and placode cells at the neural plate border of the early vertebrate embryo and investigate the molecular and environmental signals that influence specification of different sensory regions.
Factors controlling cardiac neural crest cell migration
Condensation of the neural crest cells around the aortic arch arteries and patterning depends on chemokine signaling via stromal cell-derived factor (Sdf1) and its receptor Cxcr4. 101 Cxcr4 and Sdf1 are expressed in the migrating neural crest and in the migratory pathway in the mouse and has been shown to be important for positioning of the ...
It relies on the Neural Crest Cells (NCC) colonization of the heart, whose condensation along the endocardial wall forces its scission into two tubes. Here, we show that NCC aggregation starts more pronounced at distal OFT areas than at proximal sites.
Dullard-mediated Smad1/5/8 inhibition controls mouse cardiac neural …
Feb 27, 2020 · Neural Crest Cells (NCC) colonising the heart condensate along the primitive endocardial tube and force its scission into two tubes. Here, we show that NCC aggregation progressively decreases along the OFT distal-proximal axis following a BMP signalling gradient.
Neuropilin 2/semaphorin 3F signaling is essential for cranial neural ...
In the head of vertebrate embryos, neural crest cells migrate from the neural tube into the presumptive facial region and condense to form cranial ganglia and skeletal elements in the branchial arches. We show that newly formed neural folds and migrating neural crest cells express the neuropilin 2 ( …
Transcriptional control of cardiac neural crest cells condensation …
Aug 8, 2019 · It relies on the Neural Crest Cells (NCC) colonization of the heart, whose condensation along the endocardial wall forces its scission into two tubes. Here, we show that NCC aggregation starts more pronounced at distal OFT areas than at proximal sites. This spatial organisation correlates with a decreasing distal-proximal gradient of BMP ...