The perforating dermatoses represent a group of skin disorders characterized by the "perforation," or elimination, of dermal connective tissue through the epidermis.

Reactive perforating collagenosis is the most common type of primary perforating dermatosis. It is characterised by the transepithelial elimination of collagen from the dermis through the epidermis to the skin surface.

2023年2月13日 · Traditionally, four classic forms of primary perforating dermatosis have been described: Kyrle disease, reactive perforating collagenosis, elastosis perforans serpiginosum, and perforating folliculitis. The secondary form of this condition is …

2019年3月13日 · Acquired perforating dermatosis (APD), EPS (see separate chapter) and pediatric RPC are sufficiently different to be considered independent clinical entities. Acquired perforating dermatosis (APD) is strongly associated with pruritus, chronic renal failure, and/or diabetes mellitus.

2011年7月1日 · Reactive perforating collagenosis: rare skin disease of transepidermal elimination of altered collagen via the epidermis, either inherited or acquired and associated with diabetes melliltus or end stage renal disease

2020年10月23日 · Four classical forms of primary perforating dermatosis have been described, where the transepidermal elimination mechanism represents the hallmark of the disease: acquired reactive perforating collagenosis, elastosis perforans serpiginosa, Kyrle’s …

Acquired perforating dermatosis (APD) is a rare skin condition characterized by degenerated materials eliminated from the dermis. Several retrospective studies on APD have been reported; however, few data are available on Chinese APD and their ...

2024年3月1日 · Reactive perforating collagenosis (RPC) manifests as a rare primary perforating dermatosis, showcasing distinct transepidermal elimination of modified collagen across the epidermis.

2023年2月13日 · Traditionally, 4 classical forms of primary perforating dermatosis have been described, where the transepidermal elimination mechanism represents the hallmark of the disease: Kyrle disease, reactive perforating collagenosis, elastosis perforans serpiginosum, and perforating folliculitis. [1]

The perforating dermatoses are a group of uncommon conditions characterised by the presence of keratotic papules. Some cases are associated with systemic disease, especially diabetes mellitus and renal failure.