In this review, the main features of the placenta and its derivatives such as structure, cellular composition, immunological and endocrine aspects, and the ability to invasion and deportation are discussed.

Here, we provide a snapshot of current knowledge regarding the potential of cells from the amniotic membrane of human term placenta to address current shortcomings in the field of regenerative medicine. Keywords: Placenta-derived cells, …

2024年2月24日 · Placental stem cells are cells sourced from the placenta, which is collected after delivery of full-term healthy babies. The cells are completely non-controversial. If a family does not elect to store its placenta, then it gets discarded as medical waste.

2020年9月30日 · Now, researchers have devised a way to derive and observe early precursors of placental cells in a dish. They have found a method of "reprogramming" adult cells, reverting them to a primitive state, that can prompt them to become trophoblast stem cells (TSCs), which give rise to placental cells.

Stem cell therapy is a promising approach to clinical healing in several diseases. A great variety of tissues (bone marrow, adipose tissue, and placenta) are potentially sources of stem cells. Placenta-derived stem cells (p-SCs) are in between ...

To date, MSCs have been successfully isolated from human placental villous tissue, amniotic fluid, and fetal membrane. They offer a renewable source of cell replacement for antiaging therapy, regeneration medicine, and are used to treat various neurological and immune disorders.

2022年6月29日 · This study demonstrated that CV-MSC treatment reduced proliferation, migration, angiogenic, and vasculogenic ability of TNBC cells. Additionally, treatment of cancer cells with CV-MSCs significantly decreased expression of IL-10, IL-12, CXCL9, and CXCL10 on CV-MSCs in comparison to untreated CV-MSCs.

2008年9月28日 · These two key aspects make cells from placenta good candidates for possible use in cell therapy approaches, with the possibility of providing cells that are capable of differentiating into multiple different cell types, and which also display immunological properties that would allow their use in an allo-transplantation setting.

2021年4月16日 · Placenta stem cell therapy meets all criteria for multipotent mesenchymal stromal cells based on the newest requirements given by The International Society for Cell Therapy. MMSCs are also an immune-privileged type of cell.

2015年2月3日 · Placental tissues in particular have been shown to be a rich source of stem cells with strong immunosuppressive properties, and these tissues demonstrate strong potential for cell therapy. The placenta is a unique organ of fetomaternal origin that facilitates nutrient and gas exchange between fetal and maternal blood.