Post hepatectomy liver failure (PHLF) comprises of a conundrum of symptoms and signs following major hepatic resections. The pathophysiology essentially revolves around disruption of the normal hepatocyte regeneration and disturbed liver homeostasis.

Posthepatectomy liver failure (PHLF) is a serious complication of liver surgery that occurs in about 10% of patients undergoing major liver surgery. It is the main source of morbidity and mortality. Appropriate surgical techniques and intensive care management are …

Despite important advances in many areas of hepatobiliary surgical practice during the past decades, posthepatectomy liver failure (PHLF) still represents an important clinical challenge for the hepatobiliary surgeon. The aim of this review is to present the current body of evidence regarding different aspects of PHLF.

Background: Posthepatectomy liver failure (PHLF) is a relatively rare but feared complication following liver surgery, and associated with high morbidity, mortality and cost implications.

2023年12月1日 · Post-hepatectomy liver failure (PHLF) is a leading cause of postoperative mortality after liver surgery. Due to its significant impact, it is imperative to understand the risk stratification and preventative strategies for PHLF.

2019年8月8日 · Inadequate future liver remnant volume (FLRV) can lead to post-hepatectomy liver failure (PHLF), which is a major cause of morbidity and mortality [3]. Hepatectomy, like portal vein embolization, appears to induce liver regeneration through a hyperplastic reaction [4–9].

2021年2月1日 · Post-hepatectomy liver failure (PHLF) is a feared and severe complication after liver resection and its incidence is higher after resection for hepatocellular carcinoma (HCC) and hilar cholangiocarcinoma compared to liver resection for colo-rectal liver metastases (CRLM) [6, 7], resulting in increased morbidity and mortality [3, [8], [9], [10], ...

2022年7月16日 · Post-hepatectomy liver failure (PHLF) is one of the most serious postoperative complications after hepatectomy. The aim of this study was to assess the impact of the International Study Group of Liver Surgery (ISGLS) definition of PHLF on morbidity and short- and long-term survival after major hepatectomy.

2014年8月8日 · Posthepatectomy liver failure (PHLF) is the major cause of mortality. A systemic search of Pubmed-indexed articles was done. Studies which focused on PHLF with keywords PHLF, liver failure after hepatic resection, and liver insufficiency following liver …

Background: Posthepatectomy liver failure is a feared complication after hepatic resection and a major cause of perioperative mortality. There is currently no standardized definition of posthepatectomy liver failure that allows valid comparison …