2022年11月14日 · Purkinje cells are a unique type of neuron-specific to the cerebellar cortex. They are remarkable (and instantly recognizable) for their massive, intricately branched, flat dendritic trees, which give them the ability to integrate large amounts of information and learn by remodeling their dendrites.

Purkinje cell, large neuron with many branching extensions that is found in the cortex of the cerebellum of the brain and that plays a fundamental role in controlling motor movement. These cells were first discovered in 1837 by Czech physiologist Jan Evangelista Purkinje.

2023年10月20日 · Nestled within the cerebellum, a region of the brain crucial for motor control and coordination, reside cells known as Purkinje cells. These cells are not only striking for their intricate structure but also for their profound influence on how we move and learn.

Purkinje cells are the most morphologically striking cellular elements of the cerebellar cortex. They are arranged in a single row throughout the entire cerebellar cortex between the molecular (outer) layer and the granular (inner) layer.

As the only output neurons of the cerebellar cortex, Purkinje cells are a key node in the network and, therefore, are integral to understanding cerebellar function. This review focuses on the signals represented in the discharge of Purkinje cells and what those signals tell us about cerebellar function.

Purkinje cells are important neuronal cells located in the outer layers of the cerebellum. The cerebellum is part of the brain that is primarily known for controlling sense of balance and movement but can also influence learning, memory, and mood.

2014年8月12日 · Purkinje cells, also called Purkinje neurons, are neurons in vertebrate animals located in the cerebellar cortex of the brain. Purkinje cell bodies are shaped like a flask and have many threadlike extensions called dendrites, which …

The Purkinje cells receive a direct modulatory input on their dendritic shafts from the climbing fibers, all of which arise in the inferior olive (Figure 19.8B). Each Purkinje cell receives numerous synaptic contacts from a single climbing fiber.

Purkinje cells are central to cerebellar processing as they provide the sole output of the cerebellar cortex. Furthermore, Purkinje cells are the first cerebellar cortical neurons to be born and are considered master regulators of cerebellar development based on their cellular and molecular signaling . While Purkinje cells may at first glance ...

Purkinje cells are GABAergic neurons and provide the sole output of the cerebellar cortex to the DCN and vestibular nuclei in the brain stem. Purkinje cells receive excitatory input from climbing fibers originating from the inferior olivary nucleus in the brain stem.