Rab (G-protein) - Wikipedia
Rab proteins are peripheral membrane proteins, anchored to a membrane via a lipid group covalently linked to an amino acid. Specifically, Rabs are anchored via prenyl groups on two …
Rab family of small GTPases: an updated view on their …
In this review article, we provide the most up‐to‐date and comprehensive lists of guanine nucleotide exchange factors, GTPase‐activating proteins, effectors, and knockout phenotypes …
Rab proteins as membrane organizers - Nature
2001年2月1日 · Rab proteins, which constitute the largest family of monomeric GTPases, and their effectors coordinate consecutive stages of transport, such as vesicle formation, vesicle …
Rab proteins: the key regulators of intracellular vesicle transport
2014年10月15日 · Rab proteins are characterized by their distinct sub-cellular localization and regulate a wide variety of endocytic, transcytic and exocytic transport pathways. Mutations of …
Role of Rab GTPases in Membrane Traffic and Cell Physiology
The newly synthesized Rab protein associates with Rab escort protein (REP) that directs it to Rab geranylgeranyl transferase (RabGGT) to receive its prenyl tails (red wavy lines). REP delivers …
Rab proteins and Rab-associated proteins: major actors in the …
Ras-associated binding (Rab) proteins and Rab-associated proteins are key regulators of vesicle transport, which is essential for the delivery of proteins to specific intracellular locations. More …
Rab family of GTPases - PubMed
Rab proteins represent the largest branch of the Ras-like small GTPase superfamily and there are 66 Rab genes in the human genome. They alternate between GTP- and GDP-bound states, …
Rab Protein - an overview | ScienceDirect Topics
Rab proteins are essential molecular switches in regulating virtually all membrane trafficking steps in eukaryotic cells. Rab proteins bind two operationally defined classes of proteins.
Untangling the evolution of Rab G proteins: implications of a ...
2012年8月8日 · The Rab G proteins are the single largest family of proteins that participate in the traffic between organelles, with 66 Rabs encoded in the human genome. Rabs direct the …
Rab proteins: The key regulators of intracellular vesicle transport
2014年10月15日 · Rab proteins are characterized by their distinct sub-cellular localization and regulate a wide variety of endocytic, transcytic and exocytic transport pathways. Mutations of …