Thalidomide - ALZFORUM
Thalidomide has been reintroduced and used for a number of immunological and inflammatory disorders, as well as multiple myeloma and other types of cancer. Thalidomide displays anti …
Lenalidomide - ALZFORUM
2021年4月23日 · Lenalidomide is structurally similar to thalidomide, and as such is considered a teratogen with the potential to cause birth defects and fetal death. Lenalidomide is being …
Getting to First BACE: BACE1 Inhibition Takes a Step Forward
2018年1月5日 · Banner Health is now preparing a Phase 2 clinical trial led by Shen and Sabbagh to test the effectiveness of thalidomide at lowering Aβ, sAPPβ, and BACE1 levels in plasma …
Therapeutics | ALZFORUM
2015年11月25日 · Find a Therapeutic By Name Go NSC001 AAB-003 AADvac1 AAV-GAD AAV2-BDNF ABBV-552 ABBV-916 ABT 418 ABT-089 ABT-288 ABT-384 ABT-957 ABvac40 …
Therapeutics | ALZFORUM
2015年11月25日 · Find a Therapeutic By Name Go NSC001 AAB-003 AADvac1 AAV-GAD AAV2-BDNF ABBV-552 ABBV-916 ABBV-CLS-7262 ABT 418 ABT-089 ABT-288 ABT-384 …
Timeline - Small Molecule - ALZFORUM
Small Molecule 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024
Timeline - Inflammation - ALZFORUM
Inflammation 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 2023 2024 ...
Timeline - APP and Amyloid-Related - ALZFORUM
Amyloid-Related 2000 2001 2002 2003 2004 2005 2006 2007 2008 2009 2010 2011 2012 2013 2014 2015 2016 2017 2018 2019 2020 2021 2022 ...
New Arrows Aimed at Tau: Single-Domain Antibody, Peptibody, …
2023年5月3日 · When the scientists conjugated this sdAb to thalidomide to bind E3 ubiquitin ligase and trigger degradation of the complex, the treatment nearly eliminated aggregated α …
International Conference on Alzheimer's and Parkinson's
Pumping Up Progranulin: Scientists Show New Efforts to Get It Done. 07 Apr 2023. Queen Silvia of Sweden opened the 17th International Conference on Alzheimer’s and Parkinson’s …