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In particular, a gene-dense locus on chromosome 11 (61.5–61.65 Mb) has been associated with inflammatory bowel disease, rheumatoid arthritis, and coronary artery disease. Here, we identify TMEM258 within this locus as a central regulator of intestinal inflammation.
了解详细信息:In particular, a gene-dense locus on chromosome 11 (61.5–61.65 Mb) has been associated with inflammatory bowel disease, rheumatoid arthritis, and coronary artery disease. Here, we identify TMEM258 within this locus as a central regulator of intestinal inflammation.
www.sciencedirect.com/science/article/pii/S221112…BV-2 and BW5147 cells were stably transduced with TMEM258 appended with an N-terminal V5 epitope tag. Cells were lysed (1% NP-40, PBS, pH 7.0) to generate duplicate samples containing 20 mg protein per ml of clarified lysate. TMEM258 was immunoprecipitated with 75 μl (packed volume) of anti-V5 magnetic agarose (MBL
www.cell.com/cms/10.1016/j.celrep.2016.11.042/at…TMEM258 encodes a small 76-amino acid protein containing two predicted transmembrane domains and no additional func- tional domains that can be readily identified.
www.cell.com/cell-reports/pdfExtended/S2211-124…关于 tmem258 Cytogenetic location: 11q12.2 Genomic coordinates (GRCh38): 11:61,788,949-61,792,599 (from NCBI) This gene has 8 transcripts (splice variants) and 171 orthologues.
www.medchemexpress.cn/gene/746.htmlTMEM258 (Transmembrane Protein 258) is a Protein Coding gene. Diseases associated with TMEM258 include Spinocerebellar Ataxia 20 and Chronic Laryngitis.
www.genecards.org/cgi-bin/carddisp.pl?gene=TME…跨膜蛋白 258(TMEM258)基因 | MCE - MCE-生物活性分子大师
TMEM258 Gene - GeneCards | TM258 Protein | TM258 …
2024年12月25日 · TMEM258 (Transmembrane Protein 258) is a Protein Coding gene. Diseases associated with TMEM258 include Spinocerebellar Ataxia 20 and Chronic Laryngitis.
TMEM258 Is a Component of the Oligosaccharyltransferase …
TMEM258 Is a Component of the …
2016年12月1日 · At the mechanistic level, we demonstrate that TMEM258 is a required component of the oligosaccharyltransferase complex and is essential for N-linked protein glycosylation.
TMEM258 Is a Component of the Oligosaccharyltransferase …
TMEM258 Is a Component of the ... - Broad Institute
TMEM258 protein expression summary - The Human Protein Atlas
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