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Nucleoside triphosphate - Wikipedia
A nucleoside triphosphate is a nucleoside containing a nitrogenous base bound to a 5-carbon sugar (either ribose or deoxyribose), with three phosphate groups bound to the sugar. They are the molecular precursors of both DNA and RNA, which are chains of nucleotides made through the processes of DNA replication and … 展开
The term nucleoside refers to a nitrogenous base linked to a 5-carbon sugar (either ribose or deoxyribose). Nucleotides are … 展开
Given their importance in the cell, the synthesis and degradation of nucleoside triphosphates is under tight control. This section focuses on nucleoside triphosphate metabolism … 展开
Nucleoside analogues can be used to treat viral infections. Nucleoside analogues are nucleosides that are structurally similar (analogous) to the nucleosides used in DNA and RNA synthesis. Once these nucleoside analogues enter a cell, they can become 展开
The cellular processes of DNA replication and transcription involve DNA and RNA synthesis, respectively. DNA synthesis uses dNTPs as … 展开
ATP as a source of cellular energy
ATP is the primary energy currency of the cell. Despite being synthesized through the metabolic pathway described above, it is primarily synthesized during both cellular respiration and photosynthesis by ATP synthase 展开CC-BY-SA 许可证中的维基百科文本 Polymerase incorporation of a 2′-deoxynucleoside-5′-triphosphate ...
2015年8月1日 · We investigated the enzymatic incorporation of 2′-deoxynucleoside-5′-triphosphate bearing a SB nucleobase analogue (dSBTP) into oligonucleotides (ONs) by DNA …
- 作者: Kunihiko Morihiro, Hidekazu Hoshino, Osamu Hasegawa, Yuuya Kasahara, Kohsuke Nakajima, Masayasu Kuwa...
- Publish Year: 2015
Nucleoside Triphosphates — Building Blocks for the …
This review article will focus on the recent progress made in nucleoside triphosphate synthesis and will highlight a few of the most prominent applications, including the use of modified dNTPs both as probes for unraveling the …
Biocatalytic synthesis of 2'-deoxynucleotide 5'-triphosphates from ...
2'-deoxynucleoside 5'-triphosphates (dNTPs) are the building blocks of DNA and are key reagents which are incorporated by polymerase enzymes during nucleic acid amplification techniques, …
Biocatalytic synthesis of 2′‐deoxynucleotide 5′‐triphosphates from ...
2023年3月25日 · 2′‐deoxynucleoside 5′‐triphosphates (dNTPs), generated from genomic DNA (gDNA) are demonstrated as low‐cost DNA building blocks in nucleic acid amplification. gDNA …
Deoxynucleoside triphosphate (dNTP) synthesis and destruction …
2013年8月14日 · The sterile alpha motif and HD-domain containing protein 1 (SAMHD1) protein is a deoxynucleoside triphosphohydrolase that cleaves dNTPs to the respective deoxynucleoside …
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3’-Protected 2’-Deoxynucleoside 5’-Triphosphates as a Novel …
The 5’-triphosphorylation of all 3’-protected 2’-deoxynucleoside derivatives was accomplished by the procedure described by Ludwig and Eckstein 46. The 3’-protected dNTPs were isolated in …
3'-Protected 2'-deoxynucleoside 5'-triphosphates as a tool for …
2009年6月15日 · A new approach that improves the efficiency and specificity of polymerase chain reaction (PCR) has been developed. Heat-sensitive 3'-protected derivatives of 2' …
Systematic characterization of 2′-deoxynucleoside- 5′-triphosphate ...
2006年9月29日 · We synthesized C5-modified analogs of 2′-deoxyuridine triphosphate and 2′-deoxycytidine triphosphate and investigated them as substrates for PCRs using Taq, Tth, …
2′-Deoxynucleoside 5′-triphosphates modified at α-, β- and γ …
1998年2月1日 · Abstract. Replacement of α-, β- and γ-phosphate groups in 2′-deoxynucleoside 5′-triphosphates (dNTP) with phosphonate groups yields a new set of dNTP mimic
