Rab (G-protein) - Wikipedia
Rab proteins are peripheral membrane proteins, anchored to a membrane via a lipid group covalently linked to an amino acid. Specifically, Rabs are anchored via prenyl groups on two …
Rab family of small GTPases: an updated view on their …
In this review article, we provide the most up‐to‐date and comprehensive lists of guanine nucleotide exchange factors, GTPase‐activating proteins, effectors, and knockout phenotypes …
Rab proteins as membrane organizers - Nature
2001年2月1日 · There is increasing evidence that Rab proteins and their effectors are not randomly distributed but are enriched in membrane domains, termed here Rab domains. In the …
Role of Rab GTPases in Membrane Traffic and Cell Physiology
This review comprehensively describes how Rab proteins act as molecular “switches” to regulate the formation, transport, tethering, and fusion of transport vesicles as a general mechanism for …
Rab proteins and Rab-associated proteins: major actors in the …
Ras-associated binding (Rab) proteins and Rab-associated proteins are key regulators of vesicle transport, which is essential for the delivery of proteins to specific intracellular locations. More …
Rab proteins: the key regulators of intracellular vesicle transport
2014年10月15日 · Rab proteins are characterized by their distinct sub-cellular localization and regulate a wide variety of endocytic, transcytic and exocytic transport pathways. Mutations of …
Rab proteins: The key regulators of intracellular vesicle transport
2014年10月15日 · Rab proteins are characterized by their distinct sub-cellular localization and regulate a wide variety of endocytic, transcytic and exocytic transport pathways. Mutations of …
Rab Protein - an overview | ScienceDirect Topics
Rab proteins are monomeric small guanine triphosphatases (GTPases) that function as key regulators of eukaryotic membrane trafficking. Specifically, they have been implicated in the …
Rab proteins - ScienceDirect
1998年8月14日 · Rab proteins form the largest branch of the Ras superfamily of GTPases. They are localized to the cytoplasmic face of organelles and vesicles involved in the …
Rabs and their effectors: Achieving specificity in membrane traffic
2006年8月8日 · Rab proteins constitute the largest branch of the Ras GTPase superfamily. Rabs use the guanine nucleotide-dependent switch mechanism common to the superfamily to …