The EGF receptor ligand amphiregulin controls cell division via FoxM1.
The EGF receptor ligand amphiregulin controls cell division via FoxM1.
Epidermal growth factor receptor (EGFR) is central to epithelial cell physiology, and deregulated EGFR signaling has an important role in a variety of human carcinomas. Here we show that silencing of the EGF-related factor amphiregulin (AREG) markedly inhibits the expansion of human keratinocytes through mitotic failure and accumulation of ...
vanderbilt.edu2018年8月3日
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